Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection

Coronaviruses have caused several zoonotic infections in the past two decades, leading to significant morbidity and mortality globally. Balanced regulation of cell death and inflammatory immune responses is essential to promote protection against coronavirus infection; however, the underlying mechan...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Zheng, Min, Williams, Evan Peter, Malireddi, R. K. Subbarao, Karki, Rajendra, Banoth, Balaji, Burton, Amanda, Webby, Richard, Channappanavar, Rudragouda, Jonsson, Colleen Beth, Kanneganti, Thirumala-Devi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2020
Konular:
Microbiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549031/
https://ncbi.nlm.nih.gov/pubmed/32763970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015036
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