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A novel strategy for molecular interfaces optimization: The case of Ferritin-Transferrin receptor interaction

Protein-protein interactions regulate almost all cellular functions and rely on a fine tune of surface amino acids properties involved on both molecular partners. The disruption of a molecular association can be caused even by a single residue mutation, often leading to a pathological modification o...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Di Rienzo, Lorenzo, Milanetti, Edoardo, Testi, Claudia, Montemiglio, Linda Celeste, Baiocco, Paola, Boffi, Alberto, Ruocco, Giancarlo
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7548301/
https://ncbi.nlm.nih.gov/pubmed/33101606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.09.020
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