Cryo-EM structure of the human ferritin–transferrin receptor 1 complex

Human transferrin receptor 1 (CD71) guarantees iron supply by endocytosis upon binding of iron-loaded transferrin and ferritin. Arenaviruses and the malaria parasite exploit CD71 for cell invasion and epitopes on CD71 for interaction with transferrin and pathogenic hosts were identified. Here, we pr...

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Publicat a:Nat Commun
Autors principals: Montemiglio, Linda Celeste, Testi, Claudia, Ceci, Pierpaolo, Falvo, Elisabetta, Pitea, Martina, Savino, Carmelinda, Arcovito, Alessandro, Peruzzi, Giovanna, Baiocco, Paola, Mancia, Filippo, Boffi, Alberto, des Georges, Amédée, Vallone, Beatrice
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408514/
https://ncbi.nlm.nih.gov/pubmed/30850661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09098-w
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