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Computational optimization of angiotensin-converting enzyme 2 for SARS-CoV-2 Spike molecular recognition

Since the beginning of the Covid19 pandemic, many efforts have been devoted to identifying approaches to neutralize SARS-CoV-2 replication within the host cell. A promising strategy to block the infection consists of using a mutant of the human receptor angiotensin-converting enzyme 2 (ACE2) as a de...

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Détails bibliographiques
Publié dans:Comput Struct Biotechnol J
Auteurs principaux: Di Rienzo, Lorenzo, Monti, Michele, Milanetti, Edoardo, Miotto, Mattia, Boffi, Alberto, Tartaglia, Gian Gaetano, Ruocco, Giancarlo
Format: Artigo
Langue:Inglês
Publié: Research Network of Computational and Structural Biotechnology 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8116125/
https://ncbi.nlm.nih.gov/pubmed/34002118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.05.016
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