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Template-Directed Nonenzymatic Primer Extension Using 2-Methylimidazole-Activated Morpholino Derivatives of Guanosine and Cytidine

[Image: see text] Efforts to develop self-replicating nucleic acids have led to insights into the origin of life and have also suggested potential pathways to the design of artificial life forms based on non-natural nucleic acids. The template-directed nonenzymatic polymerization of activated ribonu...

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Publicado en:J Am Chem Soc
Main Authors: Zhang, Weicheng, Pal, Ayan, Ricardo, Alonso, Szostak, Jack W.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2019
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547883/
https://ncbi.nlm.nih.gov/pubmed/31298852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b06453
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