Development of Rifapentine-Loaded PLGA-Based Nanoparticles: In vitro Characterisation and in vivo Study in Mice

BACKGROUND: Tuberculosis (TB) is a leading cause of death amongst infectious diseases. The poor response to antitubercular agents necessitates the long-term use of high drug doses, resulting in low patient compliance, which is the main reason for chemotherapy failure and contributes to the developme...

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Dades bibliogràfiques
Publicat a:Int J Nanomedicine
Autors principals: Liang, Qiuzhen, Xiang, Haibin, Li, Xinyu, Luo, Chunxia, Ma, Xuehong, Zhao, Wenhui, Chen, Jiangtao, Tian, Zheng, Li, Xinxia, Song, Xinghua
Format: Artigo
Idioma:Inglês
Publicat: Dove 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547843/
https://ncbi.nlm.nih.gov/pubmed/33116484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S257758
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