Docetaxel Loaded PEG-PLGA Nanoparticles: Optimized Drug Loading, In-vitro Cytotoxicity and In-vivo Antitumor Effect

In this study a 3-factor, 3-level Box-Behnken design was used to prepare optimized docetaxel (DTX) loaded pegylated poly lactide-co-glycolide (PEG-PLGA) Nanoparticles (NPs) with polymer concentration (X(1)), drug concentration (X(2)) and ratio of the organic to aqueous solvent (X(3)) as the independ...

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Detalhes bibliográficos
Main Authors: Noori Koopaei, Mona, Khoshayand, Mohammad Reza, Mostafavi, Seyed Hossein, Amini, Mohsen, Khorramizadeh, Mohammad Reza, Jeddi Tehrani, Mahmood, Atyabi, Fatemeh, Dinarvand, Rassoul
Formato: Artigo
Idioma:Inglês
Publicado em: Shaheed Beheshti University of Medical Sciences 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177642/
https://ncbi.nlm.nih.gov/pubmed/25276182
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