Memantine loaded PLGA PEGylated nanoparticles for Alzheimer’s disease: in vitro and in vivo characterization

BACKGROUND: Memantine, drug approved for moderate to severe Alzheimer’s disease, has not shown to be fully effective. In order to solve this issue, polylactic-co-glycolic (PLGA) nanoparticles could be a suitable solution to increase drug’s action on the target site as well as decrease adverse effect...

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Bibliografiske detaljer
Udgivet i:J Nanobiotechnology
Main Authors: Sánchez-López, Elena, Ettcheto, Miren, Egea, Maria Antonia, Espina, Marta, Cano, Amanda, Calpena, Ana Cristina, Camins, Antoni, Carmona, Nuria, Silva, Amélia M., Souto, Eliana B., García, Maria Luisa
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870370/
https://ncbi.nlm.nih.gov/pubmed/29587747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-018-0356-z
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