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Effect of apical chloride concentration on the measurement of responses to CFTR modulation in airway epithelia cultured from nasal brushings

INTRODUCTION: One method for assessing the in vitro response to CFTR‐modulating compounds is by analysis of epithelial monolayers in an Ussing chamber, where the apical and basolateral surfaces are isolated and the potential difference, short‐circuit current, and transepithelial resistance can be mo...

詳細記述

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書誌詳細
出版年:Physiol Rep
主要な著者: Bratcher, Preston E., Yadav, Sangya, Shaughnessy, Ciaran A., Thornell, Ian M., Zeitlin, Pamela L.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547589/
https://ncbi.nlm.nih.gov/pubmed/33038073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14603
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