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Effect of apical chloride concentration on the measurement of responses to CFTR modulation in airway epithelia cultured from nasal brushings

INTRODUCTION: One method for assessing the in vitro response to CFTR‐modulating compounds is by analysis of epithelial monolayers in an Ussing chamber, where the apical and basolateral surfaces are isolated and the potential difference, short‐circuit current, and transepithelial resistance can be mo...

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Библиографические подробности
Опубликовано в: :Physiol Rep
Главные авторы: Bratcher, Preston E., Yadav, Sangya, Shaughnessy, Ciaran A., Thornell, Ian M., Zeitlin, Pamela L.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547589/
https://ncbi.nlm.nih.gov/pubmed/33038073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14603
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