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Effect of apical chloride concentration on the measurement of responses to CFTR modulation in airway epithelia cultured from nasal brushings

INTRODUCTION: One method for assessing the in vitro response to CFTR‐modulating compounds is by analysis of epithelial monolayers in an Ussing chamber, where the apical and basolateral surfaces are isolated and the potential difference, short‐circuit current, and transepithelial resistance can be mo...

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書目詳細資料
發表在:Physiol Rep
Main Authors: Bratcher, Preston E., Yadav, Sangya, Shaughnessy, Ciaran A., Thornell, Ian M., Zeitlin, Pamela L.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547589/
https://ncbi.nlm.nih.gov/pubmed/33038073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14603
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