Astroglial FMRP deficiency cell-autonomously up-regulates miR-128 and disrupts developmental astroglial mGluR5 signaling

The loss of fragile X mental retardation protein (FMRP) causes fragile X syndrome (FXS), the most common inherited intellectual disability. How the loss of FMRP alters protein expression and astroglial functions remains essentially unknown. Here we showed that selective loss of astroglial FMRP in vi...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Men, Yuqin, Ye, Liang, Risgaard, Ryan D., Promes, Vanessa, Zhao, Xinyu, Paukert, Martin, Yang, Yongjie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2020
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547241/
https://ncbi.nlm.nih.gov/pubmed/32958647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2014080117
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