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Autism, Alzheimer disease, and fragile X: APP, FMRP, and mGluR5 are molecular links

The present review highlights an association between autism, Alzheimer disease (AD), and fragile X syndrome (FXS). We propose a conceptual framework involving the amyloid-β peptide (Aβ), Aβ precursor protein (APP), and fragile X mental retardation protein (FMRP) based on experimental evidence. The a...

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Detalhes bibliográficos
Main Authors: Sokol, D.K., Maloney, B., Long, J.M., Ray, B., Lahiri, D.K.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090060/
https://ncbi.nlm.nih.gov/pubmed/21482951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182166dc7
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