Suppression of inflammatory arthritis in human serum paraoxonase 1 transgenic mice

Paraoxonase 1(PON1) is an HDL-associated protein, which metabolizes inflammatory, oxidized lipids associated with atherosclerotic plaque development. Because oxidized lipid mediators have also been implicated in the pathogenesis of rheumatoid arthritis (RA), we evaluated the role of PON1 in murine i...

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發表在:Sci Rep
Main Authors: Charles-Schoeman, Christina, Wang, Jennifer, Shahbazian, Ani, Lee, Yuen Yin, Wang, Xiaoyan, Grijalva, Victor, Brahn, Ernest, Shih, Diana M., Devarajan, Asokan, Montano, Christy, Lusis, Aldons J., Reddy, Srinivasa T.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546628/
https://ncbi.nlm.nih.gov/pubmed/33033318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74016-w
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