Suppression of inflammatory arthritis in human serum paraoxonase 1 transgenic mice

Paraoxonase 1(PON1) is an HDL-associated protein, which metabolizes inflammatory, oxidized lipids associated with atherosclerotic plaque development. Because oxidized lipid mediators have also been implicated in the pathogenesis of rheumatoid arthritis (RA), we evaluated the role of PON1 in murine i...

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Publicat a:Sci Rep
Autors principals: Charles-Schoeman, Christina, Wang, Jennifer, Shahbazian, Ani, Lee, Yuen Yin, Wang, Xiaoyan, Grijalva, Victor, Brahn, Ernest, Shih, Diana M., Devarajan, Asokan, Montano, Christy, Lusis, Aldons J., Reddy, Srinivasa T.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546628/
https://ncbi.nlm.nih.gov/pubmed/33033318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74016-w
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