Suppression of inflammatory arthritis in human serum paraoxonase 1 transgenic mice

Paraoxonase 1(PON1) is an HDL-associated protein, which metabolizes inflammatory, oxidized lipids associated with atherosclerotic plaque development. Because oxidized lipid mediators have also been implicated in the pathogenesis of rheumatoid arthritis (RA), we evaluated the role of PON1 in murine i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Charles-Schoeman, Christina, Wang, Jennifer, Shahbazian, Ani, Lee, Yuen Yin, Wang, Xiaoyan, Grijalva, Victor, Brahn, Ernest, Shih, Diana M., Devarajan, Asokan, Montano, Christy, Lusis, Aldons J., Reddy, Srinivasa T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546628/
https://ncbi.nlm.nih.gov/pubmed/33033318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74016-w
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