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Inferring a complete genotype-phenotype map from a small number of measured phenotypes

Understanding evolution requires detailed knowledge of genotype-phenotype maps; however, it can be a herculean task to measure every phenotype in a combinatorial map. We have developed a computational strategy to predict the missing phenotypes from an incomplete, combinatorial genotype-phenotype map...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Sailer, Zachary R., Shafik, Sarah H., Summers, Robert L., Joule, Alex, Patterson-Robert, Alice, Martin, Rowena E., Harms, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546491/
https://ncbi.nlm.nih.gov/pubmed/32991585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008243
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