Somatic structural variation targets neurodevelopmental genes and identifies SHANK2 as a tumor suppressor in neuroblastoma

Neuroblastoma is a malignancy of the developing sympathetic nervous system that accounts for 12% of childhood cancer deaths. Like many childhood cancers, neuroblastoma shows a relative paucity of somatic single-nucleotide variants (SNVs) and small insertions and deletions (indels) compared to adult...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Lopez, Gonzalo, Conkrite, Karina L., Doepner, Miriam, Rathi, Komal S., Modi, Apexa, Vaksman, Zalman, Farra, Lance M., Hyson, Eric, Noureddine, Moataz, Wei, Jun S., Smith, Malcolm A., Asgharzadeh, Shahab, Seeger, Robert C., Khan, Javed, Auvil, Jaime Guidry, Gerhard, Daniela S., Maris, John M., Diskin, Sharon J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7545140/
https://ncbi.nlm.nih.gov/pubmed/32796005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.252106.119
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados