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Paradoxical Roles of the MAL/Tirap Adaptor in Pathologies

Toll-like receptors (TLRs) are at the forefront of pathogen recognition ensuring host fitness and eliciting protective cellular and humoral responses. Signaling pathways downstream of TLRs are tightly regulated for preventing collateral damage and loss of tolerance toward commensals. To trigger effe...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Belhaouane, Imène, Hoffmann, Eik, Chamaillard, Mathias, Brodin, Priscille, Machelart, Arnaud
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544743/
https://ncbi.nlm.nih.gov/pubmed/33072109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.569127
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