Non-Essential Role for TLR2 and Its Signaling Adaptor Mal/TIRAP in Preserving Normal Lung Architecture in Mice

Myeloid differentiation factor 88 (MyD88) and MyD88-adaptor like (Mal)/Toll-interleukin 1 receptor domain containing adaptor protein (TIRAP) play a critical role in transducing signals downstream of the Toll-like receptor (TLR) family. While genetic ablation of the TLR4/MyD88 signaling axis in mice...

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Main Authors: Ruwanpura, Saleela M., McLeod, Louise, Lilja, Andrew R., Brooks, Gavin, Dousha, Lovisa F., Seow, Huei J., Bozinovski, Steven, Vlahos, Ross, Hertzog, Paul J., Anderson, Gary P., Jenkins, Brendan J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812132/
https://ncbi.nlm.nih.gov/pubmed/24205107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078095
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