Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling

MyD88 adaptor-like (MAL) is a critical protein in innate immunity, involved in signaling by several Toll-like receptors (TLRs), key pattern recognition receptors (PRRs). Crystal structures of MAL revealed a nontypical Toll/interleukin-1 receptor (TIR)-domain fold stabilized by two disulfide bridges....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hughes, Mark M., Lavrencic, Peter, Coll, Rebecca C., Ve, Thomas, Ryan, Dylan G., Williams, Niamh C., Menon, Deepthi, Mansell, Ashley, Board, Philip G., Mobli, Mehdi, Kobe, Bostjan, O’Neill, Luke A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559006/
https://ncbi.nlm.nih.gov/pubmed/28739909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701868114
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados