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Paradoxical Roles of the MAL/Tirap Adaptor in Pathologies

Toll-like receptors (TLRs) are at the forefront of pathogen recognition ensuring host fitness and eliciting protective cellular and humoral responses. Signaling pathways downstream of TLRs are tightly regulated for preventing collateral damage and loss of tolerance toward commensals. To trigger effe...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Belhaouane, Imène, Hoffmann, Eik, Chamaillard, Mathias, Brodin, Priscille, Machelart, Arnaud
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544743/
https://ncbi.nlm.nih.gov/pubmed/33072109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.569127
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