Pre-treatment twice with liposomal clodronate protects against acetaminophen hepatotoxicity through a pre-conditioning effect

BACKGROUND AND AIM: Acetaminophen (APAP) overdose is a major cause of acute liver injury, but the role of macrophages in propagation of the hepatotoxicity is controversial. Early research revealed that macrophage inhibitors protect against APAP injury. However, later work demonstrated that macrophag...

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Detaylı Bibliyografya
Yayımlandı:Liver Res
Asıl Yazarlar: Clemens, Melissa M., Vazquez, Joel H., Kennon-McGill, Stefanie, McCullough, Sandra S., James, Laura P., McGill, Mitchell R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544241/
https://ncbi.nlm.nih.gov/pubmed/33042596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.livres.2020.07.002
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