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In situ fucosylation of the Wnt co-receptor LRP6 increases its endocytosis and reduces Wnt/β-catenin signaling
Wnt/β-catenin signaling regulates critical, context-dependent transcription in numerous physiological events. Amongst the well-documented mechanisms affecting Wnt/β-catenin activity, modification of N-glycans by L-fucose is the newest and the least understood. Using a combination of Chinese hamster...
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| Publicado no: | Cell Chem Biol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7543979/ https://ncbi.nlm.nih.gov/pubmed/32649905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2020.06.015 |
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