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The ARF GAP ELMOD2 acts with different GTPases to regulate centrosomal microtubule nucleation and cytokinesis

ELMOD2 is a ∼32 kDa protein first purified by its GTPase-activating protein (GAP) activity toward ARL2 and later shown to have uniquely broad specificity toward ARF family GTPases in in vitro assays. To begin the task of defining its functions in cells, we deleted ELMOD2 in immortalized mouse embryo...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Turn, Rachel E., East, Michael P., Prekeris, Rytis, Kahn, Richard A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7543072/
https://ncbi.nlm.nih.gov/pubmed/32614697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-01-0012
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