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The ARF GAP ELMOD2 acts with different GTPases to regulate centrosomal microtubule nucleation and cytokinesis

ELMOD2 is a ∼32 kDa protein first purified by its GTPase-activating protein (GAP) activity toward ARL2 and later shown to have uniquely broad specificity toward ARF family GTPases in in vitro assays. To begin the task of defining its functions in cells, we deleted ELMOD2 in immortalized mouse embryo...

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Pubblicato in:Mol Biol Cell
Autori principali: Turn, Rachel E., East, Michael P., Prekeris, Rytis, Kahn, Richard A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7543072/
https://ncbi.nlm.nih.gov/pubmed/32614697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-01-0012
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