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Evaluation of the rewarding effects of mitragynine and 7-hydroxymitragynine in an intracranial self-stimulation procedure in male and female rats

BACKGROUND: Kratom (Mitragyna speciosa Korth.) has been used in Southeast Asia for hundreds of years to increase energy, for relaxation, and to diminish opioid withdrawal. Kratom use has recently spread to Western countries. Kratom could potentially be used for the treatment of opioid withdrawal and...

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Publicado en:Drug Alcohol Depend
Autores principales: Behnood-Rod, Azin, Chellian, Ranjithkumar, Wilson, Ryann, Hiranita, Takato, Sharma, Abhisheak, Leon, Francisco, McCurdy, Christopher R., McMahon, Lance R., Bruijnzeel, Adriaan W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7542979/
https://ncbi.nlm.nih.gov/pubmed/32889450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2020.108235
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