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Novel Small-Molecule Inhibitor for the Oncogenic Tyrosine Phosphatase SHP2 with Anti-Breast Cancer Cell Effects
[Image: see text] The oncogenic property of the Src homology phosphotyrosine phosphatase 2 (SHP2) is well-known, but developing specific inhibitors has been very difficult. Based on our previous reports that showed the importance of acidic residues surrounding SHP2 substrate phosphotyrosines for spe...
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| Publié dans: | ACS Omega |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical Society
2020
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7542598/ https://ncbi.nlm.nih.gov/pubmed/33043190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c02746 |
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