Oleanolic Acid Decreases IL-1β-Induced Activation of Fibroblast-Like Synoviocytes via the SIRT3-NF-κB Axis in Osteoarthritis

Synovial inflammation is a major pathological feature of osteoarthritis (OA), which is a chronic degenerative joint disease. Fibroblast-like synoviocytes (FLS), localized in the synovial membrane, are specialized secretory cells. During OA synovitis, FLS produce chemokines and cytokines that stimula...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Bao, Jiapeng, Yan, Weifeng, Xu, Kai, Chen, Mengyao, Chen, Zhonggai, Ran, Jisheng, Xiong, Yan, Wu, Lidong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7542488/
https://ncbi.nlm.nih.gov/pubmed/33062145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7517219
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