Diverse Macrophage Populations Contribute to the Inflammatory Microenvironment in Premalignant Lesions During Localized Invasion

Myeloid cell heterogeneity remains poorly studied in breast cancer, and particularly in premalignancy. Here, we used single cell RNA sequencing to characterize macrophage diversity in mouse pre-invasive lesions as compared to lesions undergoing localized invasion. Several subpopulations of macrophag...

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Библиографические подробности
Опубликовано в: :Front Oncol
Главные авторы: Ibrahim, Ayman M., Moss, Matthew A., Gray, Zane, Rojo, Michelle D., Burke, Caitlin M., Schwertfeger, Kathryn L., dos Santos, Camila O., Machado, Heather L.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Oncology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541939/
https://ncbi.nlm.nih.gov/pubmed/33072601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.569985
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