Diverse Macrophage Populations Contribute to the Inflammatory Microenvironment in Premalignant Lesions During Localized Invasion

Myeloid cell heterogeneity remains poorly studied in breast cancer, and particularly in premalignancy. Here, we used single cell RNA sequencing to characterize macrophage diversity in mouse pre-invasive lesions as compared to lesions undergoing localized invasion. Several subpopulations of macrophag...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Ibrahim, Ayman M., Moss, Matthew A., Gray, Zane, Rojo, Michelle D., Burke, Caitlin M., Schwertfeger, Kathryn L., dos Santos, Camila O., Machado, Heather L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541939/
https://ncbi.nlm.nih.gov/pubmed/33072601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.569985
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