Diverse Macrophage Populations Contribute to the Inflammatory Microenvironment in Premalignant Lesions During Localized Invasion

Myeloid cell heterogeneity remains poorly studied in breast cancer, and particularly in premalignancy. Here, we used single cell RNA sequencing to characterize macrophage diversity in mouse pre-invasive lesions as compared to lesions undergoing localized invasion. Several subpopulations of macrophag...

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Vydáno v:Front Oncol
Hlavní autoři: Ibrahim, Ayman M., Moss, Matthew A., Gray, Zane, Rojo, Michelle D., Burke, Caitlin M., Schwertfeger, Kathryn L., dos Santos, Camila O., Machado, Heather L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541939/
https://ncbi.nlm.nih.gov/pubmed/33072601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.569985
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