Structural Basis of the Activation of Heterotrimeric Gs-protein by Isoproterenol-bound β(1)-Adrenergic Receptor

Cardiac disease remains the leading causes of morbidity and mortality worldwide. The β(1)-adrenergic receptor (β(1)-AR) is a major regulator of cardiac functions and is down-regulated in the majority of heart failure cases. A key physiological process is the activation of heterotrimeric G-protein Gs...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Mol Cell
Huvudupphovsmän: Su, Minfei, Zhu, Lan, Zhang, Yixiao, Paknejad, Navid, Dey, Raja, Huang, Jianyun, Lee, Ming-Yue, Williams, Dewight, Jordan, Kelsey D., Eng, Edward T., Ernst, Oliver P., Meyerson, Joel R., Hite, Richard K., Walz, Thomas, Liu, Wei, Huang, Xin-Yun
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541785/
https://ncbi.nlm.nih.gov/pubmed/32818430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.08.001
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk