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Proteasome subunits differentially control Myeloma cell viability and proteasome inhibitor sensitivity
We generated eight multiple myeloma (MM) cell lines resistant to bortezomib (BTZ); five acquired PSMB5 mutations. In 1,500 patients such mutations were rare clinically. To better understand disruption of proteasomes on MM viability and drug sensitivity, we systematically deleted the major proteasome...
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| Publicado no: | Mol Cancer Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7541608/ https://ncbi.nlm.nih.gov/pubmed/32561655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-1026 |
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