Adrenomedullin and truncated peptide adrenomedullin(22-52) affect chondrocyte response to apoptotis in vitro: downregulation of FAS protects chondrocyte from cell death

Chondrocyte apoptosis may have a pivotal role in the development of osteoarthritis. Interest has increased in the use of anti-apoptotic compounds to protect against osteoarthritis development. In this work, we investigated the effect of adrenomedullin (AM), a 52 amino-acid hormone peptide, and a 31...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Velard, Frédéric, Chatron-Colliet, Aurore, Côme, Dominique, Ah-Kioon, Marie-Dominique, Lin, Hilène, Hafsia, Narjes, Cohen-Solal, Martine, Ea, Hang-Korng, Lioté, Frédéric
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541509/
https://ncbi.nlm.nih.gov/pubmed/33028903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73924-1
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