Citrullination Is Not a Major Determinant in the Recognition of Peptidylarginine Deiminase 2 and 4 by Autoantibodies in Rheumatoid Arthritis

OBJECTIVE: Citrullinated proteins are hallmark targets of autoantibodies in rheumatoid arthritis (RA). Our goal was to determine the effect of autocitrullination on the recognition of peptidylarginine deiminase (PAD) 2 and 4 by autoantibodies in RA. METHODS: Autocitrullination sites in PAD2 and PAD4...

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Udgivet i:Arthritis Rheumatol
Main Authors: Darrah, Erika, Davis, Ryan L., Curran, Ashley M., Naik, Pooja, Chen, Ruiqiang, Na, Chan Hyun, Giles, Jon T., Andrade, Felipe
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541452/
https://ncbi.nlm.nih.gov/pubmed/32255561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41276
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