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An untargeted metabolomics strategy to measure differences in metabolite uptake and excretion by mammalian cell lines

INTRODUCTION: It is widely but erroneously believed that drugs get into cells by passing through the phospholipid bilayer portion of the plasma and other membranes. Much evidence shows, however, that this is not the case, and that drugs cross biomembranes by hitchhiking on transporters for other nat...

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Detalhes bibliográficos
Publicado no:Metabolomics
Main Authors: Wright Muelas, Marina, Roberts, Ivayla, Mughal, Farah, O’Hagan, Steve, Day, Philip J., Kell, Douglas B.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541387/
https://ncbi.nlm.nih.gov/pubmed/33026554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-020-01725-8
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