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The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data

We recently introduced the Gini coefficient (GC) for assessing the expression variation of a particular gene in a dataset, as a means of selecting improved reference genes over the cohort (‘housekeeping genes’) typically used for normalisation in expression profiling studies. Those genes (transcript...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wright Muelas, Marina, Mughal, Farah, O’Hagan, Steve, Day, Philip J., Kell, Douglas B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884504/
https://ncbi.nlm.nih.gov/pubmed/31784565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54288-7
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