Immunosuppressive role of CD11b(+)CD33(+)HLA‐DR(−) myeloid‐derived suppressor cells‐like blast subpopulation in acute myeloid leukemia

OBJECTIVE: Myeloid‐derived suppressor cells (MDSCs) facilitate tumor growth and development by suppressing T cell function; however, their role in acute myeloid leukemia (AML) remains unclear. Here, we investigated the immunosuppressive role and prognostic value of blasts with an MDSC‐like phenotype...

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Bibliografiske detaljer
Udgivet i:Cancer Med
Main Authors: Hyun, Shin Young, Na, Eun Jung, Jang, Ji Eun, Chung, Haerim, Kim, Soo Jeong, Kim, Jin Seok, Kong, Jee Hyun, Shim, Kwang Yong, Lee, Jong In, Min, Yoo Hong, Cheong, June‐Won
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Clinical Cancer Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541151/
https://ncbi.nlm.nih.gov/pubmed/32780544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3360
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