Blood CD33(+)HLA-DR(−) myeloid-derived suppressor cells are increased with age and a history of cancer

As we age, the composition of our peripheral leukocytes changes dramatically. Many of these alterations contribute to the general immune dysfunction that burdens the elderly, which in turn, contributes to increased susceptibility to disease. MDSCs represent a heterogeneous population of immunosuppre...

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Detalhes bibliográficos
Main Authors: Verschoor, Chris P., Johnstone, Jennie, Millar, Jamie, Dorrington, Michael G., Habibagahi, Mojtaba, Lelic, Alina, Loeb, Mark, Bramson, Jonathan L., Bowdish, Dawn M. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2013
Assuntos:
Translational & Clinical Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701116/
https://ncbi.nlm.nih.gov/pubmed/23341539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0912461
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