Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells

The role of endoplasmic reticulum (ER) stress in cancer has been studied in detail, and ER stress is known to increase tumor cell apoptosis, and thus, reduce tumor growth. However, in our study, persistent ER stress induced by multiple administrations of low-dose thapsigargin (Tg) accelerated tumor...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lee, Bo-Ra, Chang, Sun-Young, Hong, Eun-Hye, Kwon, Bo-Eun, Kim, Hong Min, Kim, Yeon-Jeong, Lee, Jongkook, Cho, Hyun-Jong, Cheon, Jae-Hee, Ko, Hyun-Jeong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322987/
https://ncbi.nlm.nih.gov/pubmed/25514597
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