Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells

The role of endoplasmic reticulum (ER) stress in cancer has been studied in detail, and ER stress is known to increase tumor cell apoptosis, and thus, reduce tumor growth. However, in our study, persistent ER stress induced by multiple administrations of low-dose thapsigargin (Tg) accelerated tumor...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Lee, Bo-Ra, Chang, Sun-Young, Hong, Eun-Hye, Kwon, Bo-Eun, Kim, Hong Min, Kim, Yeon-Jeong, Lee, Jongkook, Cho, Hyun-Jong, Cheon, Jae-Hee, Ko, Hyun-Jeong
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2014
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322987/
https://ncbi.nlm.nih.gov/pubmed/25514597
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