Tetrandrine sensitizes nasopharyngeal carcinoma cells to irradiation by inducing autophagy and inhibiting MEK/ERK pathway

Radioresistance was the main reason for local recurrence and metastasis of nasopharyngeal carcinoma. Tetrandrine is reported as an antitumor drug via inducing cell cycle arrest and apoptosis. In this study, the radiosensitization effects of maximum noncytotoxic doses of tetrandrine in nasopharyngeal...

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Dettagli Bibliografici
Pubblicato in:Cancer Med
Autori principali: Wang, Jun, Yao, Zhouzhou, Lai, Xiaoping, Bao, Hongwei, Li, Yue, Li, Shuaixiang, Chang, Lihong, Zhang, Gehua
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Cancer Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541130/
https://ncbi.nlm.nih.gov/pubmed/32780562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3356
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