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Chloroquine Sensitizes Nasopharyngeal Carcinoma Cells but Not Nasoepithelial Cells to Irradiation by Blocking Autophagy

BACKGROUND: Treatment of nasopharyngeal carcinoma requires the application of high dosages of radiation, leading to severe long-term complications in the majority of patients. Sensitizing tumor cells to radiation could be a means to increase the therapeutic window of radiation. Nasopharyngeal carcin...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Makowska, Anna, Eble, Michael, Prescher, Kirsten, Hoß, Mareike, Kontny, Udo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130215/
https://ncbi.nlm.nih.gov/pubmed/27902742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166766
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