Lack of airway submucosal glands impairs respiratory host defenses

Submucosal glands (SMGs) are a prominent structure that lines human cartilaginous airways. Although it has been assumed that SMGs contribute to respiratory defense, that hypothesis has gone without a direct test. Therefore, we studied pigs, which have lungs like humans, and disrupted the gene for ec...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Ostedgaard, Lynda S, Price, Margaret P, Whitworth, Kristin M, Abou Alaiwa, Mahmoud H, Fischer, Anthony J, Warrier, Akshaya, Samuel, Melissa, Spate, Lee D, Allen, Patrick D, Hilkin, Brieanna M, Romano Ibarra, Guillermo S, Ortiz Bezara, Miguel E, Goodell, Brian J, Mather, Steven E, Powers, Linda S, Stroik, Mallory R, Gansemer, Nicholas D, Hippee, Camilla E, Zarei, Keyan, Goeken, J Adam, Businga, Thomas R, Hoffman, Eric A, Meyerholz, David K, Prather, Randall S, Stoltz, David A, Welsh, Michael J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2020
Gaiak:
Medicine
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541087/
https://ncbi.nlm.nih.gov/pubmed/33026343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59653
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