Effect of murine double‐minute 2 inhibitors in preclinical models of advanced clear cell carcinomas originating from ovaries and kidneys

Advanced clear cell carcinomas originating from both ovaries and kidneys with cancerous peritonitis have poor prognoses. Murine double‐minute 2 (MDM2) is a potential therapeutic target for clear cell ovarian carcinomas with WT TP53. Herein, we characterized the antiangiogenic and antitumor effects o...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Kawata, Yoshiko, Nagasaka, Kazunori, Oda, Katsutoshi, Makii, Chinami, Takeuchi, Makoto, Oki, Shinya, Honjo, Harunori, Kojima, Machiko, Miyagawa, Yuko, Taguchi, Ayumi, Tanikawa, Michihiro, Sone, Kenbun, Hiraike, Haruko, Matsumoto, Yoko, Wada‐Hiraike, Osamu, Ayabe, Takuya, Osuga, Yutaka, Fujii, Tomoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Drug Discovery and Delivery
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541011/
https://ncbi.nlm.nih.gov/pubmed/32713096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14583
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