Effect of murine double‐minute 2 inhibitors in preclinical models of advanced clear cell carcinomas originating from ovaries and kidneys

Advanced clear cell carcinomas originating from both ovaries and kidneys with cancerous peritonitis have poor prognoses. Murine double‐minute 2 (MDM2) is a potential therapeutic target for clear cell ovarian carcinomas with WT TP53. Herein, we characterized the antiangiogenic and antitumor effects o...

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Vydáno v:Cancer Sci
Hlavní autoři: Kawata, Yoshiko, Nagasaka, Kazunori, Oda, Katsutoshi, Makii, Chinami, Takeuchi, Makoto, Oki, Shinya, Honjo, Harunori, Kojima, Machiko, Miyagawa, Yuko, Taguchi, Ayumi, Tanikawa, Michihiro, Sone, Kenbun, Hiraike, Haruko, Matsumoto, Yoko, Wada‐Hiraike, Osamu, Ayabe, Takuya, Osuga, Yutaka, Fujii, Tomoyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Drug Discovery and Delivery
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541011/
https://ncbi.nlm.nih.gov/pubmed/32713096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14583
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