Stress Signals, Mediated by Membranous Glucocorticoid Receptor, Activate PLC/PKC/GSK-3β/β-catenin Pathway to Inhibit Wound Closure

Glucocorticoids (GCs), key mediators of stress signals, are also potent wound healing inhibitors. To understand how stress signals inhibit wound healing, we investigated the role of membranous glucocorticoid receptor (mbGR) by using cell-impermeable BSA-conjugated dexamethasone. We found that mbGR i...

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Bibliografiske detaljer
Udgivet i:J Invest Dermatol
Main Authors: Jozic, Ivan, Vukelic, Sasa, Stojadinovic, Olivera, Liang, Liang, Ramirez, Horacio A., Pastar, Irena, Canic, Marjana Tomic
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540219/
https://ncbi.nlm.nih.gov/pubmed/28017831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.11.036
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