Stress Signals, Mediated by Membranous Glucocorticoid Receptor, Activate PLC/PKC/GSK-3β/β-catenin Pathway to Inhibit Wound Closure

Glucocorticoids (GCs), key mediators of stress signals, are also potent wound healing inhibitors. To understand how stress signals inhibit wound healing, we investigated the role of membranous glucocorticoid receptor (mbGR) by using cell-impermeable BSA-conjugated dexamethasone. We found that mbGR i...

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Publicado en:J Invest Dermatol
Autores principales: Jozic, Ivan, Vukelic, Sasa, Stojadinovic, Olivera, Liang, Liang, Ramirez, Horacio A., Pastar, Irena, Canic, Marjana Tomic
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540219/
https://ncbi.nlm.nih.gov/pubmed/28017831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.11.036
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