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CD47 antibody suppresses isoproterenol-induced cardiac hypertrophy through activation of autophagy

In this study, we investigated whether CD47 antibody could attenuate isoproterenol (ISO)-induced cardiac hypertrophy in mice and H9C2 cells. Cardiac hypertrophy was induced by intraperitoneal (i.p.) injection of ISO (60 mg.kg(-1).d(-1) in 100 µl of sterile normal saline) daily for 14 days, and cell...

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Bibliografische gegevens
Gepubliceerd in:Am J Transl Res
Hoofdauteurs: Li, Yong, Chen, Xuguan, Li, Peng, Xiao, Qianxuan, Hou, Daorong, Kong, Xiangqing
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540123/
https://ncbi.nlm.nih.gov/pubmed/33042468
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