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Difluoromethylornithine attenuates isoproterenol-induced cardiac hypertrophy by regulating apoptosis, autophagy and the mitochondria-associated membranes pathway

Myocardial hypertrophy is an independent risk factor of cardiovascular diseases and is closely associated with the incidence of heart failure. In the present study, we hypothesized that difluoromethylornithine (DFMO) could attenuate cardiac hypertrophy through mitochondria-associated membranes (MAM)...

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Dettagli Bibliografici
Pubblicato in:Exp Ther Med
Autori principali: Zhao, Yu, Jia, Wei-Wei, Ren, San, Xiao, Wei, Li, Guang-Wei, Jin, Li, Lin, Yan
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237397/
https://ncbi.nlm.nih.gov/pubmed/34194548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2021.10302
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