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Difluoromethylornithine attenuates isoproterenol-induced cardiac hypertrophy by regulating apoptosis, autophagy and the mitochondria-associated membranes pathway

Myocardial hypertrophy is an independent risk factor of cardiovascular diseases and is closely associated with the incidence of heart failure. In the present study, we hypothesized that difluoromethylornithine (DFMO) could attenuate cardiac hypertrophy through mitochondria-associated membranes (MAM)...

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Enregistré dans:
Détails bibliographiques
Publié dans:Exp Ther Med
Auteurs principaux: Zhao, Yu, Jia, Wei-Wei, Ren, San, Xiao, Wei, Li, Guang-Wei, Jin, Li, Lin, Yan
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237397/
https://ncbi.nlm.nih.gov/pubmed/34194548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2021.10302
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