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Difluoromethylornithine attenuates isoproterenol-induced cardiac hypertrophy by regulating apoptosis, autophagy and the mitochondria-associated membranes pathway

Myocardial hypertrophy is an independent risk factor of cardiovascular diseases and is closely associated with the incidence of heart failure. In the present study, we hypothesized that difluoromethylornithine (DFMO) could attenuate cardiac hypertrophy through mitochondria-associated membranes (MAM)...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Zhao, Yu, Jia, Wei-Wei, Ren, San, Xiao, Wei, Li, Guang-Wei, Jin, Li, Lin, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237397/
https://ncbi.nlm.nih.gov/pubmed/34194548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2021.10302
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