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The measurement of KRAS G12 mutants using multiplexed selected reaction monitoring and ion mobility mass spectrometry

RATIONALE: There is a considerable clinical demand to determine key mutations in genes involved with cancer which necessitates the deployment of highly specific and robust analytical methods. Multiplex liquid chromatography with selected reaction monitoring (LC/SRM) assays offer the ability to achie...

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書目詳細資料
發表在:Rapid Commun Mass Spectrom
Main Authors: Norman, Rachel L, Singh, Rajinder, Langridge, James I., Ng, Leong L., Jones, Donald J.L.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539944/
https://ncbi.nlm.nih.gov/pubmed/31800120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rcm.8657
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