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The measurement of KRAS G12 mutants using multiplexed selected reaction monitoring and ion mobility mass spectrometry

RATIONALE: There is a considerable clinical demand to determine key mutations in genes involved with cancer which necessitates the deployment of highly specific and robust analytical methods. Multiplex liquid chromatography with selected reaction monitoring (LC/SRM) assays offer the ability to achie...

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Detalhes bibliográficos
Publicado no:Rapid Commun Mass Spectrom
Main Authors: Norman, Rachel L, Singh, Rajinder, Langridge, James I., Ng, Leong L., Jones, Donald J.L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539944/
https://ncbi.nlm.nih.gov/pubmed/31800120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rcm.8657
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